From the North:
Leaving the A1 motorway Milan-Naples at the exit Firenze Certosa turn immediately right and take the expressway Florence-Siena. Follow this street until the exit Poggibonsi-Nord, leave the expressway here and follow the indications to San Gimignano. After the third round-about you will find, drive on for another 50 meters and then turn right in direction Ulignano-Cusona. Continue for 7 km on this street and at the stop sign in Ulignano turn right once more in direction Certaldo.
After 900 m turn left in direction S. Maria and drive for another 600 m.. and here you are at Poggio ai Cieli!

From Siena:
From the Valdichiana exit of the A1(Milano-Napoli) motorway take the expressway to Siena and when you arrive in Siena continue on this road in direction Florence until you reach the exit Poggibonsi Nord. Leave the expressway here and follow the indications for San Gimignano.  After the third round-about you will find, drive on for another 50 meters and then turn right in direction Ulignano-Cusona. Continue for 7 km on this street and at the stop sign in Ulignano turn right in direction Certaldo. After 900 m turn left in direction S. Maria and drive for another 600 m.. and here you are at Poggio ai Cieli!